Thymic epithelial cells of severe combined immunodeficiency (SCID) mice

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Thymic epithelial cells of severe combined immunodeficiency (SCID) mice.

To characterize thymic epithelial cells of SCID (severe combined immunodeficiency) mice in comparison with those of Balb C mice, we did an immunohistochemical study using cortical and medullary epithelial cell specific monoclonal antibodies (MoAbs), Th-3 and Th-4, as well as gel electrophoresis and immunoblotting. The thymi of SCID mice were composed of epithelial cells and a few lymphocytes. M...

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Because prompt intervention may prevent complications, early diagnosis is important in many inherited metabolic diseases. Early diagnosis of Severe Combined Immunodeficiency (SCID) is critical - because chances for successful treatment are highest for infants who have not yet experienced severe opportunistic infections. SCID is a rare disease that can be detected in newborn infants (i.e., those...

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ژورنال

عنوان ژورنال: Journal of Korean Medical Science

سال: 1994

ISSN: 1011-8934,1598-6357

DOI: 10.3346/jkms.1994.9.1.35